<p>Transphobia or sexual prejudice against transgender people consists of targeted hostile attitudes towards people who diverge from heterosexual pattern (Barrientos &amp; Cárdenas, 2007; Herek, 2004; 2007). Such attitudes can manifest from different dimensions -individual, government and sociocultural and environments such as familiar, political, institutional, educational, labor and social / friendships-(Blumenfeld, 1992; Cruz Sierra, 2002; Mercado, 2009 Impacting directly on public health due to the effect they have on the quality of life of transgender people through the mechanisms of exclusion and hatred for those produced (Barrientos &amp; Cárdenas, 2013; Pescoe &amp; Smart Richman, 2009). Using a qualitative methodology, an investigation is proposed using a questionnaire with open questions in order to identify the perception of transsexuality and the existence of transphobic attitudes in 29 social work students of the Universidad Autónoma de Nuevo León (México) by categorizing the questions raised. The results of this research show the number of myths, stereotypes and transphobic attitudes in the students of Social Work. That is why it is considered necessary to incorporate more formative content on sexual diversity and gender in educational schemes of Social Work programs. In order to prevent the existence of possible sources of victimization toward transgender people through professional practice.</p>